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Search Results for " muscarinic receptor "

20

Compounds

Cat No. Product Name Synonyms Targets
T11078 Deschloroclozapine Serotonin Transporter
Deschloroclozapine, a metabolite of Clozapine, is a highly potent muscarinic DREADDs agonist. Deschloroclozapine binds to DREADD receptor subtypes hM3Dq and hM4Di with Ki of 6.3 and 4.2 nM, respectively.
T1760 TBPB AChR
TBPB is an allosteric M1 mAChR agonist.
T4981 Anisotropine Methylbromide Prostaglandin Receptor , AChR
Anisotropine Methylbromide is an anticholinergic agent and has been used for relief of gastrointestinal spasm and for the suppression of gastric acid secretion.
T9419 Fesoterodine (R) Fesoterodine AChR
Fesoterodine ((R) Fesoterodine) is an orally active, competitive mAChR antagonist with pKi values of 8.0, 7.7, 7.4, 7.3, 7.5 for M1, M2, M3, M4, M5 receptors, respectively. It is used for the overactive bladder (OAB).
T7555 Piperidolate hydrochloride AChR
Piperidolate hydrochloride is an antimuscarinic, could restrain the abnormal activity caused by acetylcholine. inhibits intestinal cramp induced by acetylcholine (rats and dogs).
T23116 Oxotremorine sesquifumarate AChR
Oxotremorine sesquifumarate is a muscarinic agonist.
T8304 Anisodamine Hydrobromide 6-Hydroxyhyoscyamine Adrenergic Receptor , AChR
Anisodamine Hydrobromide (6-Hydroxyhyoscyamine) is an anticholinergic and α1-adrenergic receptor antagonist used in the treatment of acute circulatory shock.
T1281 Tropicamide Ro 1-7683 AChR
Tropicamide (Ro 1-7683) is a synthetic muscarinic antagonist with actions similar to atropine and with an anticholinergic property. Upon ocular administration, tropicamide binds to and blocks the muscarinic receptors in ...
T11095L DREADD agonist 21 5-HT Receptor , Adrenergic Receptor , AChR , Histamine Receptor
DREADD agonist 21 is a potent agonist of human muscarinic acetylcholine M3 receptors (EC50=1.7 nM).
T15942 MK-7622 M1 receptor modulator AChR
MK-7622 (M1 receptor modulator) is a modulator of muscarinic M1 receptor positive allosteric.
T9694 Emraclidine CVL-231 AChR
Emraclidine (CVL-231) is a muscarinic M4 receptor positive allosteric modulator and can be used in neurological diseases studies.
T8196 Arborine Arborin Others , AChR
Arborine (Arborin) is a larval growth inhibitor from glycoslnis pentaphylla.
T4979 Procyclidine hydrochloride (±)-Procyclidine hydrochlorid NMDAR , iGluR
Procyclidine hydrochloride ((±)-Procyclidine hydrochlorid) is a potent anticholinergic agent and also have NMDA antagonist properties.
T9353 OXOMEMAZINE AChR , Histamine Receptor
Oxomemazine is a phenothiazine-based histamine H1-receptor blocker with pronounced antimuscarinic activity. Oxomemazine is a selective antagonist of mycotoxins M1 receptors, showing high (Ki=84 nM, M1 receptors) and low ...
T6575 LY2119620 AChR
LY2119620 is a specific, and allosteric agonist of human M2 and M4 muscarinic acetylcholine receptors.
T5655 MAChR-IN-1 hydrochloride AChR
mAChR-IN-1 hydrochloride is a potent muscarinic cholinergic receptor (mAChR) antagonist, with an IC50 of 17 Nm.
T8219 VU0238441 AChR
VU0238441 is agonist of Muscarinic acetylcholine receptor M5 (human) with EC50 of 2.1μM.
T13066 TAK-071 AChR
TAK-071 is a potent, novel and highly selective modulator of muscarinic acetylcholine receptor 1 (M1R) positive allosteric(EC50 : 520 nM).
T17244 VU0467154 AChR
VU0467154 is a positive allosteric modulator of the M4 muscarinic acetylcholine receptor. The response to ACh with pEC50s of 7.75, 6.2, and 6 for a rat, human, and cynomolgus monkey M4 receptor, respectively.
T1475 Fesoterodine fumarate Toviaz,SPM 907 AChR
Fesoterodine fumarate (Toviaz) is the fumarate salt form of fesoterodine, a competitive muscarinic receptor antagonist with muscle relaxant and urinary antispasmodic properties. Fesoterodine is rapidly hydrolyzed in vivo...
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